Mushroom Spotlight: Cordyceps – Nature’s Real-Life Zombie Fungus

Dried Cordyceps mushrooms in wooden spoons on a rustic wooden surface for SmilesHigh.Club blog post about the zombie mushroom.

If there’s one mushroom that sounds like it crawled straight out of a horror movie, it’s Cordyceps. This parasitic fungus is infamous for its ability to invade the bodies of insects, take over their minds, and force them to do its bidding before erupting from their corpses like something out of an alien nightmare. If that sounds familiar, it’s because Cordyceps was the direct inspiration for the Cordyceps Brain Infection in The Last of Us. And with The Last of Us Season 2 dropping soon, it’s the perfect time to dive into the truth behind this creepy, yet fascinating, fungus.


Table of Contents

  1. The Zombie Fungus in Action
  2. Could Cordyceps Actually Infect Humans?
  3. Cordyceps in Pop Culture
  4. The Science of Fungal Mind Control
  5. MKUltra: The Government as Real-Life Cordyceps?
  6. Cordyceps: From Horror to Health Supplement
  7. The Future of Fungal Research

The Zombie Fungus in Action

There are over 600 species of Cordyceps, but the most famous is Ophiocordyceps unilateralis, which specifically targets ants. Here’s how it works:

  1. Infection – Spores land on an ant and penetrate its exoskeleton.
    Mind Control – The fungus hijacks the ant’s nervous system, compelling it to climb to an ideal height and bite onto a leaf or twig in a “death grip.”
    Body Takeover – The fungus digests the ant from the inside out, using its nutrients to grow.
    The Final Stage – A grotesque fungal stalk bursts from the ant’s head, releasing spores to infect more victims.

This process turns insects into fungus-controlled zombies—a concept so eerie that it inspired the The Last of Us franchise, which asks: What if this could happen to humans?


Could Cordyceps Actually Infect Humans?

Short answer: No… for now.

Cordyceps fungi are highly specialized, meaning they evolved to infect specific insects, not mammals. Our immune systems, body temperatures, and biology make us an unsuitable host. However, the idea of a fungal infection affecting human brains isn’t entirely impossible—some fungi, like Candida and Cryptococcus, can already infect the brain in rare cases. But don’t worry, no mind-controlling mushroom is coming for us… yet.

Close-up of a fly infected with Cordyceps fungi sprouting from its body

Cordyceps in Pop Culture

Cordyceps has fascinated scientists and storytellers alike, making its way into pop culture beyond The Last of Us:

🎮 The Last of Us (Game & HBO Series) – This post-apocalyptic world imagines a mutation of Cordyceps that infects humans, turning them into terrifying “Clickers.”
🎬 Planet Earth (BBC Documentary) – David Attenborough narrates the haunting real-life footage of Cordyceps controlling ants.
📖 The Girl with All the Gifts (Novel & Film) – A different take on fungal infections as the cause of a zombie-like pandemic.

It turns out that mushrooms can be just as terrifying in fiction as they are in reality!


The Science of Fungal Mind Control

How does Cordyceps actually hijack an insect’s brain? Scientists are still unraveling the mystery, but here’s what we know:

🧠 Chemical Manipulation – The fungus releases compounds that alter neurotransmitters, controlling behavior.
🦠 Immune System Suppression – It weakens the host’s defenses, making it easier to spread.
🕵️ Precise Genetic Targeting – Cordyceps evolved to infect specific species, ensuring its survival.

The level of control is so intricate that some scientists even call Cordyceps “nature’s most advanced bioweapon.”


MKUltra: The Government as Real-Life Cordyceps?

While Cordyceps controls insects, what if something—or someone—was trying to control us? Enter Project MKUltra, the CIA’s infamous mind-control experiments.

In the 1950s-70s, the U.S. government conducted secret experiments on unwitting citizens, attempting to manipulate minds using LSD, hypnosis, sensory deprivation, and psychological torture. The goal? To create perfect spies, soldiers, and assassins who could be programmed like puppets.

Sound familiar? Like Cordyceps hijacking ants, MKUltra sought to override free will and turn humans into mindless agents. While the program was eventually exposed, many believe similar projects still operate in the shadows today. If fungi can control bugs, and the government tried to control people… maybe the real zombie apocalypse isn’t fungal, but political.
Facebook, anybody? 😂🤨

Collage of Mark Zuckerberg as Cordyceps influencing elections with U.S. Capitol, QAnon, and Russian eagle

Cordyceps: From Horror to Health Supplement?

Despite its terrifying nature, Cordyceps is actually a superstar in traditional medicine and modern wellness. Certain species, like Cordyceps sinensis and Cordyceps militaris, have been used in Chinese medicine for centuries. Their benefits include:

✔️ Boosting Energy & Endurance – Cordyceps is popular among athletes for its potential to increase oxygen uptake.
✔️ Supporting the Immune System – It contains compounds believed to enhance immune function.
✔️ Anti-Aging & Longevity – Some studies suggest it may have anti-inflammatory and antioxidant properties.
✔️ Potential Anti-Tumor Effects – Research indicates that Cordyceps may have compounds that inhibit cancer cell growth.


The Future of Fungal Research

With fungi-based medicine and psychedelic therapy booming, Cordyceps is getting more scientific attention than ever. Researchers are exploring its applications in medicine, from anti-viral properties to performance enhancement. Plus, with its pop culture relevance in The Last of Us, Cordyceps is proving that mushrooms can be as terrifying as they are beneficial.

So, while you won’t be turning into a fungal zombie anytime soon, you might just find yourself adding Cordyceps to your supplement routine.

🍄 Stay curious, stay safe, and keep an eye on the fungi! 🍄

Scientist holding cultivated Cordyceps mushrooms in a lab for SmilesHigh.Club blog post on the zombie mushroom.

10 thoughts on “Mushroom Spotlight – Cordyceps – The Delicious Zombie Mushroom

  1. Robertabnop says:

    And THIS is why I don’t trust Big Pharma. You just KNOW someone’s trying to make a super fungus out of this.

  2. Irving Nat says:

    Okay but what’s stopping these from mutating and actually turning animals into zombies? Scientists better be keeping an eye on this.

  3. Chris T says:

    Omg this was SO interesting!! I’ve been taking cordyceps for energy but had no idea about the whole ‘zombie’ thing. Kinda freaky but also awsome

  4. Lisa Randall says:

    Love the deep dive on how Cordyceps hijacks its host’s nervous system! Fungi are seriously some of the most fascinating organisms on Earth.

  5. Jacob says:

    Broooo, this is like some straight-up sci-fi horror! Imagine if humans got infected like this… nah, I’m good. 😂

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